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Best for addressing signs of aging

M4 Face Cream

A fragrance-free restorative estriol face cream to address signs of aging like decreased collagen production, increased wrinkles, and dryness.

$149.97 ($49.99 / month)

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    Unlimited messaging with a menopause-trained doctor

Did you know?

Up to 30%

of dermal collagen is lost during the first 5 years of menopause and decreases by an additional 2.1% every year after.
Asian woman with red nail polish, hair wrapped in towel applying dots of cream to her face. AW450

Learn more about M4

What is it: M4 is a fragrance-free, prescription, estrogen-based, face cream, created specifically for perimenopausal and menopausal women. The active ingredient is topical estriol to address signs of aging.

Full list of ingredients: estriol, aloe barbadensis leaf juice , C 12 - 14 isoparaffin, caprylic/capric triglyceride, deionized water, laureth-7, phenoxyethanol, polyacrylamide, tocopheryl acetate, and triethylene glycol.

Who is it for: For any woman–really, any woman–looking to reverse the effects of estrogen-deficiency in the skin due to menopause, perimenopause, or just aging (loss of collagen, decreased elasticity and moisture, and appearance of wrinkles).

What am I getting: One bottle of M4 contains a 3-month supply (45ml).

How to get it: Prescription required. One of our menopause-trained doctors will review your medical history to determine if this is the right treatment for you.